Menopausal Arthralgia: A Pivotal Study in Singapore Reveals Key Insights

In Singapore, a groundbreaking study has brought to light that joint and muscle pain, also known as arthralgia, is the foremost menopausal symptom affecting women, a significant departure from common complaints in Western countries. The research, spearheaded by the National University Hospital (NUH) and the National University of Singapore, has shed light on the prevalence and severity of this condition among midlife women in Singapore.

Divergence from Western Data

The findings, based on two extensive studies, revealed that over two-thirds of the women experienced varying degrees of arthralgia during menopause, placing joint and muscle discomfort as the top symptom, followed by sleep problems, vaginal dryness, and mental exhaustion. Notably, the commonly recognized symptom of hot flushes ranked fifth. This stark contrast with Western data, where hot flushes are the primary complaint, underscores the geographical and possibly cultural differences in menopausal symptoms.

The Role of Oestrogen

Professor Yong Eu Long, leading the research, pointed to the decrease in oestrogen during menopause as a probable cause for the heightened arthralgia. He highlighted similarities with breast cancer patients who experience joint pain due to oestrogen inhibitors used in treatment. The protective and anti-inflammatory roles of oestrogen on joints suggest that its decline during menopause could lead to increased joint swelling, skin dryness, and muscle weakening, consequently exacerbating joint pain.

The Need for Localized Research and Awareness

The research underlines the importance of localized studies to comprehend and address the symptoms experienced by women in specific regions. Prof Yong emphasized the under-recognition of menopausal arthralgia, even among clinicians globally, and the common misinterpretation of these pains as merely signs of ageing. The poignant account of Madam Amy Fang, a study participant, highlighted the severe impact of arthralgia on daily life and the common lack of awareness about its association with menopause.

Looking Forward: Research and Interventions

The NUH team is not only bringing awareness to this overlooked issue but is also paving the way for targeted interventions. Proposed solutions include exercise regimes to strengthen muscles, thereby alleviating joint stress, and exploring the potential of menopausal hormone therapy in pain management. Upcoming studies aim to refine these approaches, offering hope to many women like Madam Fang for an improved quality of life.

The study is a call to action, emphasizing the need for more nuanced understanding and treatment of menopausal symptoms, tailored to the diverse experiences of women across the globe.